BDBM50105417 CHEMBL1089::Nardil::PHENELZINE::Phenethyl-hydrazine
SMILES NNCCc1ccccc1
InChI Key InChIKey=RMUCZJUITONUFY-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 22 hits for monomerid = 50105417
Affinity DataKi: 94nMAssay Description:Inhibition of human recombinant soluble MAO-B expressed in Pichia pastoris incubated for 30 mins prior to substrate addition measured after 60 mins b...More data for this Ligand-Target Pair
Affinity DataKi: 124nMAssay Description:Mixed-type inhibition of recombinant human MAO-B assessed as reduction in 4-hydroxyquinoline formation using varying levels of kynuramine as substrat...More data for this Ligand-Target Pair
Affinity DataKi: 163nMAssay Description:Mixed-type inhibition of recombinant human MAO-A assessed as reduction in 4-hydroxyquinoline formation using varying levels of kynuramine as substrat...More data for this Ligand-Target Pair
Affinity DataKi: 820nMpH: 7.5Assay Description:Reactions (100 µL) were initiated by the addition of 2 µL MAO-A/B (final concentrations were 100-200 nM and 0.837 µM for MAO-A and MAO...More data for this Ligand-Target Pair
Affinity DataKi: 1.20E+3nMAssay Description:Mechanism based inhibition of human cytochrome P450 2C8 measured by paclitaxel hydroxylation using a recombinant systemMore data for this Ligand-Target Pair
Affinity DataKi: 3.90E+3nMpH: 7.5Assay Description:Reactions (100 µL) were initiated by the addition of 2 µL MAO-A/B (final concentrations were 100-200 nM and 0.837 µM for MAO-A and MAO...More data for this Ligand-Target Pair
Affinity DataKi: 5.60E+3nMpH: 7.5Assay Description:Reactions (100 µL) were initiated by the addition of 2 µL of GST-LSD1 (final concentration 96-154 nM). The reaction mixture contained 50 mM...More data for this Ligand-Target Pair
Affinity DataKi: 5.60E+3nMAssay Description:Dissociation constant against galectin-3 using competitive fluorescence polarizationMore data for this Ligand-Target Pair
Affinity DataKi: 6.00E+3nMAssay Description:Inhibition of human recombinant LSD1 using H3K4me2 as substrate preincubated for 15 mins followed by substrate addition and measured after 30 mins by...More data for this Ligand-Target Pair
TargetSodium-dependent dopamine transporter(Homo sapiens (Human))
Mayo Clinic
Curated by PDSP Ki Database
Mayo Clinic
Curated by PDSP Ki Database
TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
Mayo Clinic
Curated by PDSP Ki Database
Mayo Clinic
Curated by PDSP Ki Database
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Mayo Clinic
Curated by PDSP Ki Database
Mayo Clinic
Curated by PDSP Ki Database
Affinity DataKi: 5.43E+4nMAssay Description:Mechanism based inhibition of human cytochrome P450 2C8 measured by paclitaxel hydroxylation using human liver microsomesMore data for this Ligand-Target Pair
Affinity DataIC50: 76nMAssay Description:In vitro ability of the compound to inhibit Monoamine oxidase B activity in rat whole brain in vitroMore data for this Ligand-Target Pair
Affinity DataIC50: 30nMAssay Description:In vitro ability of the compound to inhibit Monoamine oxidase A activity in rat whole brain in vitroMore data for this Ligand-Target Pair
Affinity DataIC50: 238nMAssay Description:Inhibition of recombinant human MAO-B assessed as reduction in 4-hydroxyquinoline formation using kynuramine as substrate after 20 mins by fluorometr...More data for this Ligand-Target Pair
TargetIndoleamine 2,3-dioxygenase 1(Homo sapiens (Human))
Swiss Institute Of Bioinformatics
Curated by ChEMBL
Swiss Institute Of Bioinformatics
Curated by ChEMBL
Affinity DataIC50: 1.40E+4nMAssay Description:Inhibition of IDO1 (unknown origin) using L-tryptophan substrate incubated for 60 mins by HPLCMore data for this Ligand-Target Pair
Affinity DataIC50: >8.97E+5nMAssay Description:Inhibition of human BSEP expressed in baculovirus transfected fall armyworm Sf21 cell membranes vesicles assessed as reduction in ATP-dependent [3H]-...More data for this Ligand-Target Pair
TargetMembrane primary amine oxidase(Homo sapiens (Human))
Fi-40014 University Of Jyvaskyla
Curated by ChEMBL
Fi-40014 University Of Jyvaskyla
Curated by ChEMBL
Affinity DataIC50: 19.9nMAssay Description:Inhibition of human recombinant VAP-1 expressed in CHO cells after 30 mins by coupled colorimetric methodMore data for this Ligand-Target Pair
Affinity DataIC50: 143nMAssay Description:Inhibition of recombinant human MAO-B assessed as reduction in 4-hydroxyquinoline formation using kynuramine as substrate after 20 mins by fluorometr...More data for this Ligand-Target Pair